Prolintane

This article will cover the topic of Prolintane in detail and exhaustively. Different aspects related to Prolintane will be analyzed, from its origin to its impact today. The different positions and opinions on the matter will be discussed, as well as the implications that Prolintane has in various areas of life. Through this article, we seek to provide the reader with a complete and objective vision of Prolintane, allowing them to thoroughly understand its importance and its possible implications in today's world.
Prolintane
Clinical data
Trade namesCatovit, Katovit, Promotil, Villescon
Routes of
administration
By mouth, intranasal, rectal
Drug classStimulant; Norepinephrine–dopamine reuptake inhibitor (NDRI)
ATC code
Legal status
Legal status
Identifiers
  • 1-(1-phenylpentan-2-yl)pyrrolidine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.077 Edit this at Wikidata
Chemical and physical data
FormulaC15H23N
Molar mass217.356 g·mol−1
3D model (JSmol)
Melting point133 °C (271 °F)
Boiling point153 °C (307 °F)
  • CCCC(N1CCCC1)CC2=CC=CC=C2
  • InChI=1S/C15H23N/c1-2-8-15(16-11-6-7-12-16)13-14-9-4-3-5-10-14/h3-5,9-10,15H,2,6-8,11-13H2,1H3 checkY
  • Key:OJCPSBCUMRIPFL-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Prolintane is a central nervous system (CNS) stimulant[2] and norepinephrine–dopamine reuptake inhibitor (NDRI) developed in the 1950s.[3] Being an amphetamine derivative, it is closely related in chemical structure to other drugs such as pyrovalerone, MDPV, and propylhexedrine, and has a similar mechanism of action.[4] Many cases of prolintane abuse have been reported.[5]

Under the brand name Katovit, prolintane was commercialized by the Spanish pharmaceutical company FHER until 2001. It was most often used by students and workers as a stimulant to provide energy and increase alertness and concentration.[medical citation needed]

See also

References

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. ^ Hollister LE, Gillespie HK (March–April 1970). "A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers". The Journal of Clinical Pharmacology and the Journal of New Drugs. 10 (2): 103–9. doi:10.1177/009127007001000205. PMID 4392006.
  3. ^ GB Patent 807835
  4. ^ Nicholson AN, Stone BM, Jones MM (November 1980). "Wakefullness and reduced rapid eye movement sleep: studies with prolintane and pemoline". British Journal of Clinical Pharmacology. 10 (5): 465–72. doi:10.1111/j.1365-2125.1980.tb01790.x. PMC 1430138. PMID 7437258.
  5. ^ Kyle PB, Daley WP (September 2007). "Domestic abuse of the European rave drug prolintane". Journal of Analytical Toxicology. 31 (7): 415–8. doi:10.1093/jat/31.7.415. PMID 17725890.