Small nucleolar RNA R72

In today's world, Small nucleolar RNA R72 has taken a fundamental role in our lives. From its impact on society to its influence on culture, Small nucleolar RNA R72 has had a significant impact on various aspects of daily life. As we continue to move forward into the 21st century, Small nucleolar RNA R72 continues to capture the attention of people of all ages, genders, and backgrounds. In this article, we will explore the role that Small nucleolar RNA R72 plays in our modern society, analyzing its implications and meaning in relation to different contexts and historical moments.
Small nucleolar RNA R72
Identifiers
SymbolsnoR72
RfamRF00208
Other data
RNA typeGene; snRNA; snoRNA; CD-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0001263
PDB structuresPDBe

In molecular biology, Small nucleolar RNA R72 (also known as snoR72) is a non-coding RNA (ncRNA) molecule identified in plants which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

snoR72 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]

snoR72 was originally identified in Arabidopsis thaliana and is predicted to acts as a methylation guide for 25S ribosomal RNA rRNA.[2]

References

  1. ^ Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; Presutti, C.; Bozzoni, I. (October 2002). "Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro". Molecular and Cellular Biology. 22 (19): 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMC 134041. PMID 12215523.
  2. ^ Chen CL, Liang D, Zhou H, Zhuo M, Chen YQ, Qu LH (2003). "The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa". Nucleic Acids Res. 31 (10): 2601–13. doi:10.1093/nar/gkg373. PMC 156054. PMID 12736310.