Small nucleolar RNA Me28S-Cm3227

In today's world, Small nucleolar RNA Me28S-Cm3227 is a topic of great relevance and interest to society. From its impacts on people's daily lives, to its influence on the economy and politics, Small nucleolar RNA Me28S-Cm3227 has sparked a global debate about its implications and possible solutions. In this article, we will explore the different facets of Small nucleolar RNA Me28S-Cm3227, analyzing its origin, evolution and future prospects. From its impact on mental health to its role in contemporary society, Small nucleolar RNA Me28S-Cm3227 has become an inevitably present topic in our lives, generating reflections and discussions that seek to understand its scope and consequences. Through an exhaustive analysis, this article seeks to shed light on Small nucleolar RNA Me28S-Cm3227 and offer a panoramic view that allows us to understand its importance in the current context.
Small nucleolar RNA Me28S-Cm3227
Predicted secondary structure and sequence conservation of snoMe28S-Cm3227
Identifiers
SymbolsnoMe28S-Cm3227
RfamRF00536
Other data
RNA typeGene; snRNA; snoRNA; CD-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

In molecular biology, Small nucleolar RNA Me28S-Cm3227 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA Me28S-Cm3227 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1] It is predicted that this family directs 2'-O-methylation of 28S C-3227.[2]

References

  1. ^ Galardi S, Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I (October 2002). "Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro". Molecular and Cellular Biology. 22 (19): 6663–8. doi:10.1128/MCB.22.19.6663-6668.2002. PMC 134041. PMID 12215523.
  2. ^ Huang ZP, Zhou H, He HL, Chen CL, Liang D, Qu LH (August 2005). "Genome-wide analyses of two families of snoRNA genes from Drosophila melanogaster, demonstrating the extensive utilization of introns for coding of snoRNAs". RNA. 11 (8): 1303–16. doi:10.1261/rna.2380905. PMC 1370813. PMID 15987805.


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