Nedaplatin

In today's article we are going to delve into the fascinating world of Nedaplatin. We will explore its origins, its evolution over time, its impact on current society and its possible future implications. From its inception to its current state, Nedaplatin has played a crucial role in various aspects of human life, and it is important to understand its importance to better understand the world around us. Throughout this article, we will examine Nedaplatin from different perspectives and offer a detailed analysis of its influence in today's world. Get ready to embark on a journey of discovery and learning about Nedaplatin!

Nedaplatin
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		IV
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • Diammineplatinum
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC2H8N2O3Pt
Molar mass303.181 g·mol−1
3D model (JSmol)
  • C(C(=O)).N.N.

  • coordination form: O=C1O()()OC1
  • InChI=1S/C2H3O3.2H3N.Pt/c3-1-2(4)5;;;/h1H2,(H,4,5);2*1H3;/q-1;;;+2/p-1
  • Key:GYAVMUDJCHAASE-UHFFFAOYSA-M
  (verify)

Nedaplatin (INN, marketed under the tradename Aqupla) is a platinum-based antineoplastic drug which is used for cancer chemotherapy. The complex consists of two ammine ligands and the dianion derived from glycolic acid.

Platinum-based drugs are widely employed as antineoplastic agents, especially cisplatin and carboplatin. Due to issues of their toxicity and number of cisplatin-resistant cancer cells, other platinum derivatives have been developed. Nedaplatin is one example of such new drugs.

References

  1. ^ Apps MG, Choi EH, Wheate NJ (August 2015). "The state-of-play and future of platinum drugs". Endocrine-Related Cancer. 22 (4): R219-33. doi:10.1530/ERC-15-0237. hdl:2123/24426. PMID 26113607.
  2. ^ Johnstone TC, Park GY, Lippard SJ (January 2014). "Understanding and improving platinum anticancer drugs--phenanthriplatin". Anticancer Research. 34 (1): 471–6. PMC 3937549. PMID 24403503.

External links

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