Desmoplastic fibroma

In this article, we will explore the fascinating world of Desmoplastic fibroma, a topic that has captured the attention of countless individuals throughout history. From its origins to its relevance today, Desmoplastic fibroma has played a significant role in various spheres of life. Through detailed analysis, we will examine the different facets of Desmoplastic fibroma, highlighting its impact on society, culture and science. With a retrospective and prospective look, this article seeks to provide a comprehensive understanding of Desmoplastic fibroma and its influence on the contemporary world.
Desmoplastic fibroma
SpecialtyOncology

In medicine, a desmoplastic fibroma is a low-grade malignant, locally aggressive, fibrous and rare tumor of the bone, affecting children and young adults, potentially resulting in cortical bone destruction. It usually affects craniofacial bones, mandible most frequently, long bones (metaphyseal femur, tibia, humerus).[1] The World Health Organization, 2020, reclassified these tumors as specific benign tumors in the category of fibroblastic and myofibroblastic tumors.[2]

Although it does not tend to metastatize, it has a high local recurrence and infiltrative growth.[3] Treatment consists in wide local excision to prevent otherwise frequent recurrences.[4] The role of radiotherapy and chemotherapy in this tumor still is unclear.[5]

Some cases have been described, in which an osteosarcoma has arisen from a desmoplastic fibroma.[6]

A famous occurrence of this particular form of the disease involved Italo-Australian Riccardo Torresan in 2011, with 18 cm of femur needing to be removed with the now widely recognized method of "aggressive curettage" being employed.[7]

See also

References

  1. ^ "Desmoplastic Firboma".
  2. ^ Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". Pathologica. 113 (2): 70–84. doi:10.32074/1591-951X-213. PMC 8167394. PMID 33179614.
  3. ^ Schneider, M.; Zimmermann, A. C.; Depprich, R. A.; Kübler, N. R.; Engers, R.; Naujoks, C. D.; Handschel, J. (2009). "Desmoplastic fibroma of the mandible - review of the literature and presentation of a rare case". Head & Face Medicine. 5: 25. doi:10.1186/1746-160X-5-25. PMC 2787487. PMID 19930688.
  4. ^ "Desmoplastic fibroma".
  5. ^ "Desmoplastic fibroma".
  6. ^ Abdelwahab, Ibrahim Fikry; Klein, Michael J.; Hermann, George; Steiner, German C.; Yang, David C. (2002). "Osteosarcoma Arising in a Desmoplastic Fibroma of the Proximal Tibia". American Journal of Roentgenology. 178 (3): 613–615. doi:10.2214/ajr.178.3.1780613. PMID 11856684.
  7. ^ "Desmoplastic Fibroma - BONETUMOR.ORG".


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