Cortical pseudolaminar necrosis
Nowadays, Cortical pseudolaminar necrosis is a topic that has captured the attention of many people around the world. With the advancement of technology and globalization, Cortical pseudolaminar necrosis has become an important part of our lives. With this in mind, it is crucial to understand the importance and relevance of Cortical pseudolaminar necrosis in today's society. Throughout this article, we will explore different aspects of Cortical pseudolaminar necrosis and its impact in different areas, from economics to culture. Likewise, we will analyze the role that Cortical pseudolaminar necrosis plays in people's daily lives and how it is shaping the future. Without a doubt, Cortical pseudolaminar necrosis is an issue that we cannot ignore, and it is crucial to be aware of its implications and consequences.
Cortical pseudolaminar necrosis, also known as cortical laminar necrosis and simply laminar necrosis, is the death of cells in the cerebral cortex of the brain in a band-like pattern, with a relative preservation of cells immediately adjacent to the meninges.
It is seen in the context of cerebral hypoxic-ischemic insults, e.g. status epilepticus, strokes.
Histologically, grey matter is more vulnerable than white matter to necrosis due to lack of oxygen. The third layer of the grey matter is the most vulnerable. Damage is greater in the sulci when compared to gyri of the brain.
When seen on CT scan, it shows hyperdensity in the surface of the cortex. Cortical enhancement is seen after two weeks, with maximum intensity at one to two months, and resolved after six months.
On MRI scans, early changes show low T1 intensity due to ischemic changes. There is high T1 intensity due to accumulation of neuronal damage, reactive tissue changes, and deposition of fat-laden macrophages.
See also
References
- ^ Hypoxic and Ischemic Encephalopathy. neuropathology.neoucom.edu. Accessed on: 29 December 2010.
- ^ a b c d Samain, J.; Haven, F.; Gille, M.; Mathys, P. (2011-06-18). "Typical CT and MRI features of cortical laminar necrosis". Journal of the Belgian Society of Radiology. 94 (6): 357. doi:10.5334/jbr-btr.713. ISSN 2514-8281. PMID 22338400.
External links
- Hypoxic-ischemic encephalopathy - principles (neuropathology-web.org)
- Laminar necrosis on MRI (rochester.edu)
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