Acylpyruvate hydrolase

Today we want to talk about Acylpyruvate hydrolase, a topic that has generated interest and controversy over time. Acylpyruvate hydrolase is a matter that has been talked about in different areas and that has generated conflicting opinions. Throughout history, Acylpyruvate hydrolase has been the object of study, debate and analysis, since its relevance and impact are undeniable. In this article we will explore different aspects related to Acylpyruvate hydrolase, from its origin to its influence today. In addition, we will seek to understand the importance of Acylpyruvate hydrolase and how it has marked a before and after in various contexts. Without a doubt, Acylpyruvate hydrolase is a topic that does not leave anyone indifferent and that will continue to generate interest in the future.
acylpyruvate hydrolase
Identifiers
EC no.3.7.1.5
CAS no.54004-67-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, an acylpyruvate hydrolase (EC 3.7.1.5) is an enzyme that catalyzes the chemical reaction

a 3-acylpyruvate + H2O a carboxylate + pyruvate

Thus, the two substrates of this enzyme are 3-acylpyruvate and water, whereas its two products are carboxylate and pyruvate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 3-acylpyruvate acylhydrolase. This enzyme participates in tyrosine metabolism.

References

  • Watson GK, Houghton C, Cain RB (1974). "Microbial metabolism of the pyridine ring. The metabolism of pyridine-3,4-diol (3,4-dihydroxypyridine) by Agrobacterium sp". Biochem. J. 140 (2): 277–92. PMC 1167999. PMID 4375963.