ADB-FUBHQUCA

In today's world, ADB-FUBHQUCA is a topic that has sparked a lot of interest and debate. From its origins to its evolution today, ADB-FUBHQUCA has had a significant impact on various areas of society. Its influence has extended to aspects such as economics, politics, culture and technology, generating both admiration and controversy. In this article, we will explore in depth the various aspects related to ADB-FUBHQUCA, analyzing its impact in different contexts and examining the implications it has today.

ADB-FUBHQUCA
Identifiers
  • (S)-N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1,4-dihydroquinoline-3-carboxamide
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H26FN3O2
Molar mass395.478 g·mol−1
3D model (JSmol)
  • NC(=O)(NC(=O)C=1Cc2ccccc2N(C=1)Cc1ccc(F)cc1)C(C)(C)C
  • InChI=1S/C23H26FN3O2/c1-23(2,3)20(21(25)28)26-22(29)17-12-16-6-4-5-7-19(16)27(14-17)13-15-8-10-18(24)11-9-15/h4-11,14,20H,12-13H2,1-3H3,(H2,25,28)(H,26,29)
  • Key:WEFDGWANUSMUJL-UHFFFAOYSA-N

ADB-FUBHQUCA is a synthetic cannabinoid receptor agonist that has been sold as a designer drug, first reported in 2022. It is related to the previously reported compound ADB-FUBICA but with the central indole ring system expanded to a 1,4-dihydroquinoline structure. This breaks the aromaticity of the ring system, and ADB-FUBHQUCA is relatively low in potency compared to related compounds where the aromatic core is retained.

See also

References

  1. ^ "New Substance Report. 118. ADB-FUBHQUCA". AIPSIN monitoring (in Russian). 18 February 2022.
  2. ^ "Cumyl-PeGaClone and other recently encountered synthetic cannabinoid receptor agonists. A review of the evidence on their use and harms" (PDF). Advisory Council on the Misuse of Drugs. Government Digital Service, UK Government. 2022.
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  6. ^ Manera C, Benetti V, Castelli MP, Cavallini T, Lazzarotti S, Pibiri F, et al. (October 2006). "Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists". Journal of Medicinal Chemistry. 49 (20): 5947–5957. doi:10.1021/jm0603466. PMID 17004710.
  7. ^ Stern E, Muccioli GG, Bosier B, Hamtiaux L, Millet R, Poupaert JH, et al. (November 2007). "Pharmacomodulations around the 4-oxo-1,4-dihydroquinoline-3-carboxamides, a class of potent CB2-selective cannabinoid receptor ligands: consequences in receptor affinity and functionality". Journal of Medicinal Chemistry. 50 (22): 5471–5484. doi:10.1021/jm070387h. PMID 17915849.
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